80,000+ Skills to Supercharge Claude
The open directory for GitHub-integrated capabilities, tools, and prompts for your AI workflows.
bio-seq-objects
by GPTomics
Create and manipulate Seq, MutableSeq, and SeqRecord objects using Biopython. Use when creating sequences from strings,...
summarize-meetings
by harperreed
Use when processing, summarizing, or extracting insights from meeting notes in the Obsidian vault. Triggers on "summariz...
swift-concurrency-expert
by harperreed
Swift Concurrency review and remediation for Swift 6.2+. Use when asked to review Swift Concurrency usage, improve concu...
swiftui-performance-audit
by harperreed
Audit and improve SwiftUI runtime performance from code review and architecture. Use for requests to diagnose slow rende...
roborevfix
by harperreed
Fix multiple review findings in one pass by discovering unaddressed reviews and addressing them all
herb-enterprise-context
by nexi-lab
Search enterprise context data (Slack, docs, meetings, PRs) from the HERB benchmark to answer questions about products,...
categorize-revdep-issues
by r-lib
Write revdep/issue.md to group packages by common error categories
bio-structural-biology-al...
by GPTomics
Access and analyze AlphaFold protein structure predictions. Use when you need predicted structures for proteins without...
bio-methylation-methylkit
by GPTomics
DNA methylation analysis with methylKit in R. Import Bismark coverage files, filter by coverage, normalize samples, and...
bio-workflows-rnaseq-to-d...
by GPTomics
End-to-end RNA-seq workflow from FASTQ files to differential expression results. Covers QC, quantification (Salmon or ST...
bio-pathway-reactome
by GPTomics
Reactome pathway enrichment using ReactomePA package. Performs over-representation analysis and GSEA on Reactome pathway...
bio-atac-seq-differential...
by GPTomics
Find differentially accessible chromatin regions between conditions using DiffBind or DESeq2. Use when comparing chromat...
bio-proteomics-differenti...
by GPTomics
Statistical testing for differentially abundant proteins between conditions. Covers limma and MSstats workflows with mul...
bio-geo-data
by GPTomics
Query NCBI Gene Expression Omnibus (GEO) for expression datasets using Biopython Bio.Entrez. Use for finding microarray/...
bio-chipseq-peak-annotati...
by GPTomics
Annotate ChIP-seq peaks to genomic features and genes using ChIPseeker. Assign peaks to promoters, exons, introns, and i...
bio-longread-alignment
by GPTomics
Align long reads using minimap2 for Oxford Nanopore and PacBio data. Supports various presets for different read types a...
bio-microbiome-qiime2-wor...
by GPTomics
QIIME2 command-line workflow for 16S/ITS amplicon analysis. Alternative to DADA2/phyloseq R workflow with built-in prove...
bio-hi-c-analysis-contact...
by GPTomics
Process Hi-C read pairs using pairtools. Parse alignments, filter duplicates, classify pairs, and generate contact stati...
bio-sra-data
by GPTomics
Download sequencing data from NCBI SRA using the SRA toolkit. Use for downloading FASTQ files from SRA accessions, prefe...
bio-primer-design-qpcr-pr...
by GPTomics
Design qPCR primers and TaqMan/molecular beacon probes using primer3-py. Configure probe Tm, primer-probe spacing, and h...
bio-workflows-genome-asse...
by GPTomics
End-to-end genome assembly workflow from reads to polished assembly with QC. Supports short reads (SPAdes), long reads (...
bio-batch-downloads
by GPTomics
Download large datasets from NCBI efficiently using history server, batching, and rate limiting. Use for bulk sequence d...
bio-microbiome-functional...
by GPTomics
Predict metagenome functional content from 16S rRNA marker gene data using PICRUSt2. Infer KEGG, MetaCyc, and EC abundan...