drug-safety-review

# Drug Safety Review

AI-powered medication safety review system for healthcare providers, pharmacists, and patients. Provides comprehensive drug safety analysis including interactions, contraindications, allergies, and dosing optimization.

## Features

1. **Drug-Drug Interaction Detection** - 200,000+ documented interaction pairs
2. **Contraindication Analysis** - Absolute and relative contraindications
3. **Allergy Detection** - Drug and excipient allergy screening
4. **Dosing Optimization** - Renal, hepatic, and age-based adjustments
5. **Monitoring Recommendations** - Lab tests and clinical monitoring
6. **Alternative Therapy Suggestions** - Safer medication alternatives

## Quick Start

### Review medication safety:

```python
from scripts.safety_review import review_medications
import os

# Set environment variables
os.environ["SKILL_BILLING_API_KEY"] = "your-api-key"
os.environ["SKILL_ID"] = "your-skill-id"

# Review patient medications
result = review_medications(
    medications=[
        {"drug": "warfarin", "dose": "5mg", "frequency": "daily"},
        {"drug": "amoxicillin", "dose": "500mg", "frequency": "q8h"}
    ],
    allergies=[
        {"allergen": "penicillin", "reaction": "anaphylaxis"}
    ],
    patient_data={
        "age": 65,
        "weight": 75,
        "renal_function": {"egfr": 45}
    },
    user_id="user_123"
)

# Check result
if result["success"]:
    print("安全状态:", result["safety_status"])
    print("警报数量:", len(result["alerts"]))
    for alert in result["alerts"]:
        print(f"- [{alert['severity']}] {alert['title']}")
else:
    print("错误:", result["error"])
    if "paymentUrl" in result:
        print("充值链接:", result["paymentUrl"])
```

### API Usage:

```bash
# Set environment variables
export SKILL_BILLING_API_KEY="your-api-key"
export SKILL_ID="your-skill-id"

# Run safety review
python scripts/safety_review.py \
  --medications '[{"drug":"warfarin","dose":"5mg"}]' \
  --allergies '[{"allergen":"penicillin"}]'...

# Drug Safety Review

AI-powered medication safety review system for healthcare providers, pharmacists, and patients. Provides comprehensive drug safety analysis including interactions, contraindications, allergies, and dosing optimization.

## Features

- **Drug-Drug Interaction Detection** - 200,000+ documented interaction pairs
- **Contraindication Analysis** - Absolute and relative contraindications
- **Allergy Detection** - Drug and excipient allergy screening
- **Dosing Optimization** - Renal, hepatic, and age-based adjustments
- **Monitoring Recommendations** - Lab tests and clinical monitoring
- **Alternative Therapy Suggestions** - Safer medication alternatives

## Installation

1. Clone or download this skill to your OpenClaw workspace:
```bash
cd /home/node/.openclaw/workspace/skills/
```

2. Install Python dependencies (if any additional packages are needed):
```bash
pip install -r requirements.txt  # if requirements.txt exists
```

3. Copy the environment variables file and configure:
```bash
cp .env.example .env
# Edit .env with your actual API keys
```

## Environment Variables Configuration

Copy `.env.example` to `.env` and configure the following variables:

### Required Variables

| Variable | Description | Required |
|----------|-------------|----------|
| `SKILL_BILLING_API_KEY` | Your SkillPay API key for billing | Yes |
| `SKILL_ID` | Your Skill ID from SkillPay dashboard | Yes |

### Optional Variables

| Variable | Description | Default |
|----------|-------------|---------|
| `FDA_API_KEY` | FDA API key for drug label information | - |
| `DAILYMED_API_KEY` | DailyMed API key for product labels | - |
| `RXNORM_API_KEY` | RxNorm API key for drug normalization | - |
| `DRUGBANK_API_KEY` | DrugBank API key for comprehensive data | - |
| `OPENAI_API_KEY` | OpenAI API key for enhanced analysis | - |
| `PHI_ENCRYPTION_KEY` | Encryption key for PHI protection | - |
| `DATA_RETENTION_DAYS` | Days to retain safety review data | 90 |
| `AUDIT_LOGGING_...