OpenClaw

clarity-submit

Submit a protein variant hypothesis to Clarity Protocol for validation and folding. Use when the user asks to submit a hypothesis, propose a protein variant, queue a fold, or investigate a mutation. Requires CLARITY_WRITE_KEY env var. Capabilities: submit hypothesis, check submission status.

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查看来源 ↗安装与使用 SKILL.md ↗

安装与使用

请根据来源仓库和你的 AI 工具说明安装此技能。先阅读技能文件和依赖要求，再添加到工作流。

SkillHub CLI

skillhub install clarityprotocol/clarity-submit

打开来源仓库，查看说明和兼容环境后，按来源提供的命令或步骤安装。

将来源链接提供给你的 Agent，让它先读取说明、核对依赖，并向你说明将执行的安装步骤。

查看来源 ↗使用指南

技能说明

Clarity Submit Skill

Submit protein variant hypotheses to Clarity Protocol for automated validation and ColabFold structural prediction.

Quick Start

Submit a hypothesis:

python scripts/submit_hypothesis.py --protein SOD1 --variant A4V --rationale "ALS-linked mutation with unknown structural impact"

Submit with optional fields:

python scripts/submit_hypothesis.py --protein MAPT --variant P301L --rationale "Tau pathology in frontotemporal dementia" --wallet "YOUR_SOLANA_WALLET"

Check hypothesis status:

python scripts/check_status.py --id 42

Setup

Set your write API key:

export CLARITY_WRITE_KEY=your_write_key_here

Contact the Clarity Protocol team to request a write API key.

What Happens After Submission

Feasibility validation runs automatically against UniProt, ClinVar, gnomAD, and PubMed
If validated, the hypothesis is auto-queued for ColabFold structural prediction
Four AI research agents continuously monitor the variant for new findings
Results are available at the tracking URL returned after submission

Request Fields

--protein (required): Protein name (e.g., SOD1, MAPT, APP, SNCA)
--variant (required): Variant notation (e.g., A4V, P301L, G2019S)
--rationale (required): Why this variant is worth investigating (min 10 characters)
--disease (optional): Disease area (auto-detected from protein if omitted)
--wallet (optional): Solana wallet address for $FOLD reward eligibility

Response Fields

id: Unique hypothesis identifier
protein_name: Normalized protein name
variant_notation: Variant as submitted
status: Current status (submitted, validating, validated, queued, folding, complete, rejected)
tracking_url: URL to track progress on clarityprotocol.io

Rate Limits

Write (POST): 10 submissions per day per key
Read (GET): 100 requests per minute per key

Size Limits

Proteins up to 1,500 residues can be folded....

来源信息

Source: github
Repository: openclaw/skills
Path: skills/clarityprotocol/clarity-submit
Version: —
Commit: 6dca7eb21f683d60492cd3b67168e7d1f9c971e5
分类来源: rules
状态: active
可见性: public

这些信息来自收录时的来源分析，可能滞后；使用前请核对最新来源文件。

来源内容

SKILL.md

# Clarity Submit Skill

Submit protein variant hypotheses to Clarity Protocol for automated validation and ColabFold structural prediction.

## Quick Start

Submit a hypothesis:

```bash
python scripts/submit_hypothesis.py --protein SOD1 --variant A4V --rationale "ALS-linked mutation with unknown structural impact"
```

Submit with optional fields:

```bash
python scripts/submit_hypothesis.py --protein MAPT --variant P301L --rationale "Tau pathology in frontotemporal dementia" --wallet "YOUR_SOLANA_WALLET"
```

Check hypothesis status:

```bash
python scripts/check_status.py --id 42
```

## Setup

Set your write API key:

```bash
export CLARITY_WRITE_KEY=your_write_key_here
```

Contact the Clarity Protocol team to request a write API key.

## What Happens After Submission

1. **Feasibility validation** runs automatically against UniProt, ClinVar, gnomAD, and PubMed
2. If validated, the hypothesis is **auto-queued** for ColabFold structural prediction
3. Four AI research agents continuously monitor the variant for new findings
4. Results are available at the tracking URL returned after submission

## Request Fields

- `--protein` (required): Protein name (e.g., SOD1, MAPT, APP, SNCA)
- `--variant` (required): Variant notation (e.g., A4V, P301L, G2019S)
- `--rationale` (required): Why this variant is worth investigating (min 10 characters)
- `--disease` (optional): Disease area (auto-detected from protein if omitted)
- `--wallet` (optional): Solana wallet address for $FOLD reward eligibility

## Response Fields

- `id`: Unique hypothesis identifier
- `protein_name`: Normalized protein name
- `variant_notation`: Variant as submitted
- `status`: Current status (submitted, validating, validated, queued, folding, complete, rejected)
- `tracking_url`: URL to track progress on clarityprotocol.io

## Rate Limits

- **Write (POST)**: 10 submissions per day per key
- **Read (GET)**: 100 requests per minute per key

## Size Limits

Proteins up to 1,500 residues can be folded....

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