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solublempnn

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.

adaptyvbio☆ 91 Repository stars7 Repository forks

Installation

Follow the repository instructions for this skill and your agent. Review the files and dependencies before adding it to your workflow.

View source ↗Guides

Skill instructions

Features and purpose

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.

Quick start

Follow the repository instructions for this skill and your agent. Review the files and dependencies before adding it to your workflow.

Guides ↗

Examples

Read the usage examples in the source repository.

View source ↗

Source history

Indexed on
2026-01-20
Index updated
2026-02-07
Branch
main

Index and sync dates describe this directory. View the source repository for code history.

GitHub ↗

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