80,000+ Skills to Supercharge Claude
The open directory for GitHub-integrated capabilities, tools, and prompts for your AI workflows.
bio-flow-cytometry-fcs-ha...
by GPTomics
Read and manipulate Flow Cytometry Standard (FCS) files. Covers loading data, accessing parameters, and basic data explo...
bio-pathway-gsea
by GPTomics
Gene Set Enrichment Analysis using clusterProfiler gseGO and gseKEGG. Uses a ranked gene list to find coordinated change...
bio-transcription-transla...
by GPTomics
Transcribe DNA to RNA and translate to protein using Biopython. Use when converting between DNA, RNA, and protein sequen...
bio-alignment-msa-parsing
by GPTomics
Parse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze g...
bio-population-genetics-l...
by GPTomics
Calculate linkage disequilibrium statistics (r², D'), perform LD pruning for population structure analysis, identify hap...
bio-proteomics-data-impor...
by GPTomics
Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant prote...
bio-pathway-wikipathways
by GPTomics
WikiPathways enrichment using clusterProfiler and rWikiPathways. Performs over-representation analysis and GSEA on commu...
bio-spatial-transcriptomi...
by GPTomics
Compute spatial statistics for spatial transcriptomics data using Squidpy. Calculate Moran's I, Geary's C, spatial autoc...
bio-rna-quantification-al...
by GPTomics
Quantify transcript expression using pseudo-alignment with Salmon or kallisto. Use for fast, accurate transcript-level q...
bio-metabolomics-pathway-...
by GPTomics
Map metabolites to biological pathways using KEGG, Reactome, and MetaboAnalyst. Perform pathway enrichment and topology...
bio-read-alignment-bwa-al...
by GPTomics
Align DNA short reads to reference genomes using bwa-mem2, the faster successor to BWA-MEM. Use for whole genome sequenc...
bio-metagenomics-amr-dete...
by GPTomics
Detect antimicrobial resistance genes using AMRFinderPlus, ResFinder, and CARD. Screen isolates and metagenomes for resi...
bio-single-cell-data-io
by GPTomics
Read, write, and create single-cell data objects using Seurat (R) and Scanpy (Python). Use for loading 10X Genomics data...
bio-de-deseq2-basics
by GPTomics
Perform differential expression analysis using DESeq2 in R/Bioconductor. Use for analyzing RNA-seq count data, creating...
bio-alignment-statistics
by GPTomics
Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity m...
bio-single-cell-clusterin...
by GPTomics
Dimensionality reduction and clustering for single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for running PC...
bio-hi-c-analysis-compart...
by GPTomics
Detect A/B compartments from Hi-C data using cooltools and eigenvector decomposition. Identify active (A) and inactive (...
bio-restriction-mapping
by GPTomics
Create restriction maps showing enzyme cut positions on DNA sequences using Biopython Bio.Restriction. Visualize cut sit...
bio-copy-number-cnv-visua...
by GPTomics
Visualize copy number profiles, segments, and compare across samples. Create publication-quality plots of CNV data from...
bio-blast-searches
by GPTomics
Run remote BLAST searches against NCBI databases using Biopython Bio.Blast. Use for sequence similarity searches, identi...
bio-variant-calling-deepv...
by GPTomics
Deep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Il...
bio-population-genetics-s...
by GPTomics
Python population genetics with scikit-allel. Read VCF files, compute allele frequencies, calculate diversity statistics...
bio-pdb-geometric-analysi...
by GPTomics
Perform geometric calculations on protein structures using Biopython Bio.PDB. Use for measuring distances, angles, and d...
bio-population-genetics-s...
by GPTomics
Detect signatures of natural selection using Fst, Tajima's D, iHS, XP-EHH, and other selection statistics. Calculate pop...